You could go with many early Neo Geo AES games but I'm going with Last Resort. From the opening stage city backdrop is inspired by Akira. Detailed sprites. Many layers. Huge sprites on bosses. This was beyond the puny 16-bit consoles. This was a 24-bit monster. Thunder Force IV thinks it looks good?! pfft Last Resort spits all over it! Last Resort comes on a 45 Megabit Cartridge!