One that is in the works that I anticipate the most is Gothic Remake - Gothic started back in late 90s as "let's try to make something like Ultima VII, but in 3D", and while it's quite playable til this day, even for someone like me, who really loves it, can be rough around the edges in many aspects. It seems that studio making the remake is listening to fan's feedback, so I'm cautiously optimistic about it.
That said, it's exactly Ultima (IV-VII) that I'd want to see being remade the most, preferably in the style of classic isometric CPRGs.