Slightly a case of "what I've played" - man, I've played some bad games from that year - but I'm giving it to Angry Birds, for the whole franchise. Gaming history doesn't have many big puzzle series: Lemmings, AB and... The Incredible Machine is sadly forgotten. Seriously, what other series than Lemmings and Worms can you compare AB to?
(I've always wished they'd make Angry Birds vs Worms crossover.)
Honorary mention to Tom Clancy's H.A.W.X. - I do like action flight sims.