FF13, but only if it's either a playable demo or gameplay footage. Cutscenes won't be a showstealer this time out.
Failing that:
I'm leaning towards God of War 3 or LBP for Sony, and either a new Zelda or Kid Icarus on the Nintendo side, and Fable 2 or Alan Wake on 360.
Wild cards as surprise 'winner' of the show would be one of those two unknown PS3 IP's(I'm pulling for Team ICO), Heavy Rain, or a new Wii peripheral.
Too hard to gauge what the media reaction will be. For me, personally, I'll say God of War 3.







