For me it would have to be Xenoblade Chronicles, released in NA in 2012, long after the Wii’s heyday. To me, it’s one of the best RPGs ever made, with a great narrative, outstanding music, extraordinary size and scope, and amazingly deep role-playing mechanics.
Another favorite of mine: Donkey Kong Country 3 from 1996. I love it in particular for its overworld and secrets, in addition to its rock-solid 2D platforming and jaw-dropping graphics.