I think my realistic hardware hopes would be kind of like this:
CPU: 6 Core Arm CPU
GPU: 1024 Ampere Cuda cores min with DLSS/RT
Vram: 8GB LPDDR5X (1GB for OS and 7GB for games)
SSD: 256GB min with at least 500MB/s read/write
Screen: 1080p IPS panel
Battery: 40Wh
Dock: HDMI 2.1 + Ethernet Port + USB
CPU: I don't think any more CPU horse power than 6 cores is necessary. Maybe they can do also do 4 big and 4 small or 6 big or 2 small.
GPU: I highly doubt it will have 2048 as that sounds like a lot of cuda cores to fit into a small device.
Vram: Series S has 8GB of Vram LPDDR5X, the Switch certainly doesn't need more but I really hope Nintendo doesn't put less.
SSD: While 500mb/s might sound slow, we have seen based off of DFs videos on Unreal Engine that Streaming assets largely scales with resolution. As most
games will be running at 720p-1080p, not much reason to put in a faster but more expensive SSD.
Screen: Personally, I think a 720p screen is that I think it's the perfect PPI to performance sweet spot for a device like this. Based on the Steam Decks performance, it's able to be faster than a PS4 if the PS4 is running the game at 1080p while Steam Deck is running the same game at 800p/720p. But if the Steam Deck runs the game at 1080p, it's slower. OLED will also increase the cost too much and while I would like to have a 1080p screen, upscaling games from 720p to 1080p will look worse than running Native. But if the Switch 2 really has DLSS, then upscaling from 720p to 1080p should be pretty good.
Battery: The switch currently has a 4310mAh but I'd like them to increase it to 5,313mAh which is about what Steam Deck has.
Dock: Please by the love of god include the Ethernet Port at a minimum.
PC Specs: CPU: 7800X3D || GPU: Strix 4090 || RAM: 32GB DDR5 6000 || Main SSD: WD 2TB SN850
