As far as industry changing games....
Has to be blizzard. War craft was big for the rts genre and mmo... Then starcraft came along and did it again.
Not to mention Dota began as a war craft mod, helping usher in a new gaming genre. While blizzard didn't do it, they created the tools and resources so that someone could. Hell, dota had a even more basic version of some sort in StarCraft too if I recall correctly...
Diablo... Probably their best ip imo also was pretty industry changing.
I'll say that donkey Kong also was very impactful but didn't really help spawn a new genre. Just massively improved the existing formula.
Goldeneye though showed that console fps could work, perfect dark built on that and was a much more refined experience.
Have to give it to blizzard though.