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I have to be honest, I'm a bit confused on what you're talking about here. I finished the original RE1 for the first time a few months ago and:

1 ) Zombies do NOT respawn. The most you'll get is a zombie getting back up after you've only hurt it a bit, or new zombies populating an area (I honestly can't remember if this is a mechanic in RE1 though, I know it is in RE2, if it is in RE1 it's super scripted and not really a natural gameplay mechanic)

2 ) Unlike its REmake, RE1 (and really all the PS1 RE games) actively encourages you to use ammo and just kill the zombies. It's actually one of the few things I found to be a huge disappointment going back from REmake, zombies are almost always guaranteed to die in 3-4 hits from your pistol, whereas in REmake it's much more randomized.

That being said, OG RE1 is harder than OG RE2 by far and probably harder than OG RE3 if you don't include the gimmicky Nemesis battles, so I can understand having some difficulties. To me, REmake made it a very easy game because that game is so much more methodical.

Edit: I'm pretty sure in OG RE1 the only time the mansion might "repopulate" is when you go back to the mansion and the hunters are activated, even then I'm not sure if those are new zombies though or just the hunters themselves 

Last edited by AngryLittleAlchemist - on 24 August 2021