The first three games in the series were some of my favorite games from my childhood. Breath of Fire 2 and 3 were my introduction into the idea that religion and/or god could be antagonists in a story.
I've been hoping for a new game in the series ever since BoF 5. From what I've seen BoF 6 should hardly count as a mainline entry in the series, and even that is many years old.
If they were to release a new entry then I'd buy it in a second.