It wouldn't surprise me if it's a remake of one of the previous games.
That said, if it's a new game, I hope they put more effort in it and manage to beat Saints Row The Third (for me, the best one).
Honestly though, it was the best one. Saints Row IV got boring once you had all the powers and you were pretty much invincible. I never played the second SR so I can't criticise that, but the first one was alright. No Professor Genki's magically appearing in it ): I never finished Gat out of Hell because it was lame when I started playing it. It didn't appeal to me like SR3 did, never kept my interest. I also missed the creativity of making your own character.
If there is a new game, I want more challenges involving Professor Genki, hands down. But I don't think there will be a new game to be honest.
If you require alcohol to have fun, then you have a problem