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Shadow1980 said:
Depends. Are they an attractive humanoid and have the same... naughty bits that we do? If so, yeah, I would. It would be impossible to have kids with them, which may or may not be a plus, and certainly any diseases attuned to a species to radically different genetically (despite the convergent morphological evolution) would be unlikely to cross over (you'd be more likely to contract tobacco mosaic virus from a plant and have it make you sick). This means sex would likely be less risky than it would be with another human.

That's right, If life on the home planet of the alien is based on different Amino acids than life on Earth, we would be probably immune to all diseases the alien might have. You have to be careful about the ph-value of the alien genitals because it could potentially be very painful