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Sordel said:
The right answer is Tetris. Looking back over the years, I'd also have to mention Bravely Default & Advance Wars.

Persona 4 Golden is essentially a port from PS2 and therefore shouldn't count, great though it is.

"While versions of Tetris were sold for a range of 1980s home computer platforms as well as arcades, it was the successful handheld version for the Game Boy launched in 1989"