One thing I have to say is that I'm genuinely impressed how much I care about the characters in the story. For the most part, the story missions are kind of tepid and boring, but the characters themselves are great. Which is surprising because I usually have a hard time caring about game characters. I think the reason is that you have a lot of moments that humanize them. For example, helping Mary find her younger brother Jamie. I genuinely felt a lot of warmth when Jamie hugged Arthur like family - or the final scene when Mary is near speechless and gets on the train. It was like Arthur was a father figure, or at least an uncle, to Jamie. And it was so cuuuuteee when Arthur went on a fishing trip with young Jack 
(makes me want to finish the OG game and finally play Undead Nightmare, which I never played).
I think a lot of it is down to the fact that the game contextualizes it better than most other story-driven titles on the market. You don't care about the characters because the game designers force you to watch some cutscenes. You care about them because you come home to see them every few hours.
Although I will admit, I can only remember a few names off hand that aren't the main protagonist - Charles, Lenny, Dutch, Hosea, John, Micah, but that's more of a problem with there being so many characters (and me being bad at remembering names). It does feel a little like they just took every stereotype possible and made a character out of them to fill a huge roster, rather than make a few characters mixed with various stereotypes. But still, pretty impressed on that front - that I actually care about some of the characters.
Also if anyone knows a good free video hosting site for small clips, I have some great Red Dead 2 clips 
