My Friend Pedro is by far the one I'm anticipating the most.
Sable is a close second that takes some inspirations from Breath of the Wild, but its development kinda concerns me so I try not to get too excited about it;
The Gardens Between looks cool;
Gato Roboto and GRIS are two really cool games that came out of Gamescom;
Wargroove I think is on everyone's radar for quality indie games