As a programmer I say it is possible - with cutbacks like Wolfenstein or Doom. It is more a question of: how much cutbacks and how much work to port. I think sales should justify that in the case of MonHun.
60fps games, get massive resolution degrade, texture degrade, effects ect... and its playable at HALF the FPS on the Switch.
Im not sure MHW would turn out great.
Would you play a MHW that runs half the resolution of the PS4, and 15 fps capped? with certain effects dialed back? and lesser textures ect.
if so then yes, the Switch *could* run such a MHW.
Necro-bump this 2020: http://gamrconnect.vgchartz.com/thread.php?id=229249
Bumb in 2021: http://gamrconnect.vgchartz.com/post.php?id=9047071