As a programmer I say it is possible - with cutbacks like Wolfenstein or Doom. It is more a question of: how much cutbacks and how much work to port. I think sales should justify that in the case of MonHun.
You mean halving the framrate? 13fps fun! xD
The next game should be built from the ground up to support ALL systems, including switch. Porting MHW isn't feasible, just as porting Witcher 3 or Farcry 5 isn't.