That it looks to be a good successor of Theme Hospital is something obvious from the start. After all, some of the devs behind this game were also the ones behind Theme Hospital.
But so far we've only seen impressions from short demos and a handfuil of missions. We still don't know if the game will be fun for long plays or only for small bursts.
That's why I also trust them all the more, since they previously worked on the original title, so they the knowledge and experience needed to make this a decent successor to the original game. That and they don't have a publisher like EA to twist their arms and demolish their projects.
Well the original had it's own missions and it is a game about managing a hospital as well as staff and patients with made up illnesses, there isn't much to go with beyond that