Lets Look at the 2007 Box office top 20:
- Spider Man 3
- Shrek the Third
- Transformers
- Pirates of the Caribbean: At World's End
- Harry Potter and the Order of the Pheonix
- I am Legend
- The Bourne Ultimatum
- National Treasure: Book of Secrets
- Alvin and the Chipmunks
- 300
- Ratatouille
- The Simpsons Movie
- Wild Hogs
- Knocked Up
- Juno
- Rush Hour 3
- Live Free or Die Hard
- Fantastic Four: Rise of the Silver Surfer
- American Gangster
- Enchanted
The only movies on that list that are not well known based on a movie, television show, comic book or novel would be Ratatouille, Wild Hogs, Knocked Up, Juno, American Gangster and Enchanted. If you look at how much "Star Power" was brought to most of these movies based on the studios working on them or the actors involved about the only one that could be considered a break-out success would be Juno ...
Most people favour entertainment that they're familiar with, which means that it is amazingly hard to see a break out success.