It'd really surprise me if Sony *did not* have something new and big to announce. 2-3-4 years ago the tank was full of gas (GoW, TLG, FFXV, UC4) - now nearly all the big PS4 titles have almost all released.
Stuck thinking on what exactly that might be. My best guess might be a new DMC or some exclusive Star Wars game.
I would think re-upping PSVR support is in the cards too
I predict NX launches in 2017 - not 2016