Where in the world is this coming from?
I feel too old for random sex so I still just call it VD if speaking in generalities otherwise I'm more specific and say for instance "I heard she has the clap" or a more specific real life example. There is a girl in our town that looks quite a bit like Megan Fox (nice body too) and we call her GBH it stands for German Baptist Herpes.
Edit: GBH ... what a shame, she's fucking hot.