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This is difficult because it is one thing to introduce IP and it is another for those IP to get their foundations set.

Kirby was introduced on the GB, but one can argue it wasn't until his NES or SNES game that the franchise hit its style of game that has helped produce titles even until this day. With Nintendo there are a number of franchises that have had similar stories so I personally will abstain because depending on definition of 'introduction' this could mean way different things plus the question is hard depending on what titles you like.

 

Edit: Also Advance Wars originated on the Famicom as Famicom Wars. Just like Fire Emblem, it was just never released and rarely mentioned until the GBA version was brought over.