On your first time through a game...well, once you've hit a wall and seem stuck long enough ("long enough" being a time determined by the individual), I see no harm in looking at a guide to keep progressing. I can think of quite a few examples of NES games where I wouldn't have moved past a spot without clarification from an outside source (tip book, playground chatter, etc.)
On a replay, bust that guide open. A replay means I really love a game and want to see all it has to offer, and often a guide is the only way to do that due to missable elements.







