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superchunk said:

So, purely hypothetical mental model that looks at the most plausible scenario is one based on science, not religion, that kills off humanity. Unless an alien race kills us off because their religion says they are the only true beings of God.

You're basing your whole hypothetical model on the belief that killing off humanity completely is the worst thing that can happen when it's not.

I'd say the finality of human extinction is better than the slow and extended suffering caused by religion-justified irrationality.