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Sounds good, but I would probably get a higher-clocked dual-core versus a lower-clocked quad-core - there will be few games, even in years to come, that actually use all four cores to exceed the performance of that dual-core. You may even want to go for a budget CPU (honestly, it won't make much difference to games or work; they're all good at the moment) and get a 4870 or GTX 260 when they come out.

Is 8GB of RAM necessary? You won't see any benefit above 4GB.

It would be wise to wait for actual reviews of the 4850/4870 vs. the GTX260/280. Although, prelimenary bechmarks and prices show the 4850 CF to exceed a GTX280 for the same price, so an ATI setup will always give the best performance at a given price point.