I think so. Assassin's creed 2 and Brotherhood (even revelations) are the most well-known chapters here in Italy. Are also the best chapters in the whole series for critics and public, especially the protagonist Ezio Auditore which has been "abused" by Ubisoft for it's popularity, but there still a huge gap in popularity.
An other exapmple could be Shadow of Rome which is popular in Italy despite it's low sales.







