To be cartoon and anime are two different things
Cartoons which i would say are up there
Ducktales
Jetsons
Flintstones
Gargoyles
Anime
One Piece - i only started watching it in 2015 was never into long anime as generally lot of filler crap but One Piece has held out very well. I can see it going forever tbh lol.
Full Metal Alchemist
Cowboy Bebop
these are probably my top three but plenty other worth watching.