I didn't play Ocarina of Time until I got it for free on Gamecube. It was still, at the time, the greatest game I'd ever played!
I didn't play Minish Cap until maybe last year. Again, I was blown away.
I also didn't play Link's Awakening until maybe a year or two ago. Fantastic game and I regret never playing it when it first released. All of this new 8th gen tech I have and I couldn't think of anything but a Gameboy Color title for days!