This might be an unpopular opinion, but Insomniac has always struck me as a developer very good at creating a game based on an already well established formula. They've never really created something that really pushes the boundaries and limits of the genre. That's not to say they don't make good games. I love the stuff they put out.
With that said, the way Resistance 2 seems to be shaping up, it appears that Insomniac is finally pushing the gameplay envelope. The squad based 64 man multiplayer matches in particular sound amazing. Throw in two campaigns with one being online-enabled for 4 players, and you've got the making for something that might be able to compare to COD4.
My Top 5:
Shadow of the Colossus, Metal Gear Solid 3, Shenmue, Skies of Arcadia, Chrono Trigger
My 2 nex-gen systems: PS3 
and Wii 
Prediction Aug '08: We see the PSP2 released fall '09. Graphically, it's basically the same as the current system. UMD drive ditched and replaced by 4-8gb on board flash memory. Other upgrades: 2nd analog nub, touchscreen, blutooth, motion sensor. Design: Flip-style or slider. Size: Think Iphone. Cost: $199. Will be profitable on day 1.
