In the technical side, no, his decision basically got rid of the small chance of humanity finally being able to suffer no more, and have a much bbetter chance of surviving.
Joel is only human though, and Ellie was like a second daughter to him, especially after everything that happened during the Winter chapter.
A good amount of people would probably say if they were in Joel's position, they would simply let Ellie go for the sake of saving lives, but not a lot of people can say they had their daughter die in their hands, and then find a close person that fills that very empty void.
Ugh, I used to hate TLOU, and thought it was overrated trash. I still think it's overrated, but I appreciate the game much more than I used to.
"Just for comparison Uncharted 4 was 20x bigger than Splatoon 2. This shows the huge difference between Sony's first-party games and Nintendo's first-party games."