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Erik Aston said:
Too many lists without Guitar Hero.

I'm not sure why you would measure things by first week sales, either.

I'd put Mario at #1 in overall popularity. There could be FIVE 10-million selling Mario games this gen alone by this time next year. (NSMB, MK DS, MK Wii, SMG, M&S@O.) Already 65M games sold this gen.

Then Wii-brand, Pokemon, the Sims, GTA, Brain Training and Guitar Hero round out the top. Halo, CoD and Animal Crossing could be up there, but they both only have 1 recent mega-hit. Madden, FIFA, Need for Speed, Final Fantasy and Zelda are probably still in the top 20. Warcraft has to be put up there. A potential top 20 franchise people might not think of is LEGO Star Wars, which has sold 18M units in just over 3 years.

 

I'm using that criteria because I'm more interest in franchises that can sell over one million first week than franchises  that are known with long legs. This is why I need an edit button.

This is why Animal Crossing, or any of the EA stuff wouldn't count because I really doubt they could hit a million.