I'd say it depends on the drug.
Soft drugs like cannabis have a lot of benefits to legalizing them and only very few drawbacks. A controlled market, ensures better quality, healthy tax inflow, more jobs and less crime.
Hard drugs would need prescriptions imo, wich again leads to problems with corruption and black markets all over again.
At the same time I don't think Heroin, Chrystal Meth or MDMA should be sold over the counter.
Heavy adics should be able to get prescriptions to clean needles and clean drugs, but their use needs to be monitored, and they shouldn't be allowed to take care of children. (We had some horrific cases of child neglect and even children dying of overdose because they took their foster parents drugs.)
So hard drugs would aways come with big costs attached to them, even if they were legalized.
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