I don't think anyone can separate Kojima from the Metal Gear Solid series, but even then where will they take it? The series went into a full circle, and the last chapter featured a tangent story line with a few connections to future events.
Metal Gear Solid was basically Kojima's whole career and making a game without his direction would most likely produce a game that won't sit well with the fans, especially after Konami fired and relocated most of their important staff.
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