Nautilus on 03 August 2015
If that happens, it may take awhile for they start developing it, since Camelot is busy making the new Mario Tennis(correct me if im wrong).But i do agree with you, Nintendo needs to bring it back.And having Isaac in Smash would be a great marketing for the series, to make more people aware of the franchise.
My (locked) thread about how difficulty should be a decision for the developers, not the gamers.
https://gamrconnect.vgchartz.com/thread.php?id=241866&page=1
