Uncharted: The Nathan Drake Collection leaked via mobile PlayStation store!

[Hynad]

o_O.Q said:

Faelco said:

It's exactly that. Uncharted 4 is supposed to be the end of Nathan's adventures ("A thief's end"), it will be better if the players like the character. And even if I like him, he's not as well known as Lara Croft for example. They have to work on that. 

that has not been confirmed it could mean another character involved inthe story

They have confirmed that this game will bring closure to Nathan Drake's character.

 

Watch the interview. Druckmann mentions it at the end of it. That's one example. There are a few others such examples in which Naughty Dog mentions that Uncharted 4 will be the last game in the series.