May sound weird, but the controller for my OUYA felt best in my hand of all controllers ever (also got lucky and no problems at all with it), maybe because I got very long fingers which keep getting in the way with each other on many other controllers (especially Playstation's Dualshocks, all of them). The Wii U Gamepad comes second, as again no risk tangling up my fingers here, but I dislike the arragement of the right thumbstick above the buttons instead of below. Last but not least comes the Xbox controller, which lies very good in my hand, although it could be a bit bigger for me.
And none of them beats a good keyboard & mouse combo ;)







