Vaccination doesn't require mandates.
Just ensure that everybody is well-educated, and say "okay you have the right to not vaccinate your child, but not doing so prevents your child from entering public education". Private schools will also have the right to reject non-vaccinated kids.
If said parents still choose to not vaccinate and home school, once the child is old enough to make their own decisions, they should be well within the right to elect to have vaccinations. There's no age limit on vaccinations, as far as I'm aware?
EDIT: Personally, when it comes to my children. They will have all the recommended vaccinations, but I would like the say over the speed and frequency at which they occur. Having several in a short period of time doesn't sit right with me, and I would prefer to spread them out a little.
