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Falcon Talons from Ninja Gaiden 2/Sigma 2.

Agni and Rudra from DMC3.

Double Enforcers from Unreal Tournament series.

*edit*

Shotguns or various representations of shotguns from various games.  On some games you don't even have to be close range for these weapons to be amazing.  Unreal Tournament's Flak Cannon, etc.  They're my favorite weapons types in Uncharted series, Armored Core series, and Army of Two.