It's been stated on the PS Blog that Ratchet & Clank for PS4 will get it's first glimpses of gameplay this fall, if I had to bet this would be where that will happen.
It's possible Media Molecule's new IP could be unveiled here as the 1st party title that Tidux was talking about and MM have said that details about the game will be given soon.
Uncharted usually always gets something of gameplay shown towards the end of the year before the year it comes out, so it's likely Uncharted 4 could be shown.
GT7 could be unveiled here.
I think Destination Playstation does usually have some good announcements, so it's a good bet at least one or two new games will be announced, whether it be exclusives, multiplats or new gameplay for games already announced.
