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It's a tough call. My money is on Splatoon, because I think it's going to catch on. It a pretty novel shooter. That said, Mario Maker has a lot of potential, depending on how much Nintendo puts into it. It may also be the cheapest on top of that, which could help it. However it might be digital only, which could hurt it. Yoshi is tried and true and this looks like it has the makings of a top notch Yoshi game. Whether it sells millions or not, it probably deserves to.