Most likely Starfox Wii
F-Zero is possible, but I don't know if they'd consider it a big title like this.
I don't know if Pilotwings has ever been big enough to warrant such praise either.
The Next Zelda for the Wii is still too far off yet.
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P.S. Its easier to say the PS3 has more quality games when it announces its games three years in advance and the Wii won't announce its until 6 months before release. Even if you could argue the PS3 has more quality titles, don't expect that to last. The PS3's AAA line up so far has been relatively mediocre anyway, you won't see serious quality games until GT5, MGS4 or FFXIII. Resistance was admitted by the Sony fandom to be a so-so game when it came out and they only clung to it as a savior later in lieu of nothing else to tide them over. Motorstorm is about as revolutionary as Excite Truck. LAIR was a bomb. Heavenly Sword was only five hours long and was something few wished to delve upon a month after its launch. Ratchet and Clank is a luke warm foot note that has come and gone. Uncharted is a great game, but it plays it so safe by copying other genres and formulas its really hard to consider it a unique game. To quote a great game reviewer, Uncharted pushes the envelope about as much as if you were to set an envelope in front of a Glacier. As far as I can tell Sony was trying to pre-empt RE5 in making a game where you shoot up minorities in an uncivilized setting.
