I've finished all four Uncharted games on crushing difficulty and the only one I find to be much of a problem is Uncharted Golden Abyss where there's an ever so slight input lag. I got used to the input lag where I can aim and target fine even on a faster speed, but it was irritating until I got used to it.
I know what people are talking about on Uncharted 3 how moving the targetting diagonally wasn't smooth until they patched it, but I had no problem with it. It's already patched so any issue someone has with it now unless they have the same issue with Uncharted 2 is a completely baseless claim.
*edit*
Also, here's a tip on Uncharted when shooting. If you try to go for 100% hit ratio, and fire a shot here and there, you're going to be missing more often than not if you don't get a head shot. Get used to firing repeated shots with a pistol or a machine gun, as sthis way, you hit your target once, you'll hit them repeatedly. If you're playing online, then you have to use a bit more skill obviously, as hitting someone only slightly slows them down. Also, if you're playing online now and you're joining a game by yourself, you're more than likely going to end up on a team of stragglers versus a few good people or a clan that's paired up on the other team.
