Best case is a bit of a silly thing to ask for... I mean BEST case scenario I can see the Mario Skylander figures taking off, along with them making a super cheap version of the hardware turn it into a platform for parents to buy children for the whole skylaner/disney infinite/new mario figures thing.
If Nintendo was smart they'd even promote some exclusiveness with these products.
That could actually move a lot of backend product like the gamecube did with it's pricecut to a higher degree.
Will that LIKELY happen?
No. It's a way they could go though, that might work.
Likely best case scenario... eh 20 Mil maybe?