Albicant on 21 January 2014
It's a bit early to see what kind of influence GTAV will have.
Tough to argue with the OP - CoD4, for better or for worse, was an insurmountable presence this gen, it really shaped the landscape.
Uncharted 2 would probably be next up, though a fair distance behind. The game's outstanding cinematography, set pieces, story-gameplay balance etc have definitely shown their influence.
Don't really see Xenoblade or Mario Galaxy as having demonstrated major influence. Not sure about RDR as I don't play many sand box games, but in other genres I haven't noticed RDR casting many shadows.
Of those games excluded from the poll, most influential would have to be Wii Sports and Wii Fitness..
