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Science is based on a lot of assumptions yes.

It's something people should keep in mind, because we generally know a lot less about shit then you'd think we do. Even things as basic as medical care are a lot less certain then you'd think.

Is it based too much on assumptions?

No, because it's based on the minimum amount of assumptions possible.

It's just there is a shitload of them because we don't know shit about shit.