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1. Colonies on the Moon or in space and hopefully people landing on Mars by then.

2. Cure for Cancer

3. Cars that don't run on gasoline as the norm.

4. A better government and a better way to elect officials.

5. American obesity actually dropping

 

I know some of these aren't very exciting and I love technological advances but I shudder to think how anti-social and awkward people will be in 50 years compared to now when you can't even hold a conversation with someone without them looking on their smartphones all the time.