I play on a 92" 1080p projector screen and on a 15.4" 1080p laptop screen, with both I prefer native 1080p without AA over any upscaling solutions with AA.
Native resolution instantly looks better on an LCD screen, much easier on the eyes without the softness introduced by upscaling. I actually rather take a frame rate hit instead of dropping resolution.
Down sampling from 4K is even better but I don't have the capable hardware for that. I can make screenshots that way, but playing at 5 fps isn't a lot of fun.
AA solutions aren't always that great either, they easily miss sub pixel detail popping in and out. 4xmsaa doesn't always make it look better. 4xfsaa is the only thing that really works, which is the same as rendering at 4K and down sampling to 1080p (or is 4xfsaa at 1080p rendering at 8K, I can never remember if it's 4x the pixels, or 4x the width and 4x the height)







