Kid Icarus, even if it is just a suped up port of Uprising, so long as its battle mode and the controls for the touch screen (or being able to use the second analog) are improved.
Trauma Center/Team, I'd love to see one these, I hate that I won't get another chance at fake surgery all while hokey anime junk goes on around me.
Hotel Dusk/Last Window, a great mystery game series that I wish Nintendo would give another chance to, although I get that the original developers have already been shut down.
EX Troopers, Capcom botched this aiming it exclusively after the Japanese audience when they could have gotten more cash with a international release. A enhanced Wii U version released in the West should draw more interest especially with a Western release and given the lack of Wii U titles of its type.