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It will probably sell best on the XBox 360 because it already has a larger userbase in North America and it is $200 cheaper (meaning that it will be the obvious choice for someone who is picking up the system to play the game); on top of that Halo 3 will be one of the biggest games this year and there are a lot of people who will be interested in both games.

At the same time, I fully expect GTA 4 to be one of the lowest selling GTA games because the combined userbase of the PS3 and XBox 360 is smaller than the userbase for the PS2 when GTA 3 was released; and even with a price reduction these systems are still too expensive to buy for one game.