Well, it may not be of the same magnitude but Super Mario Galaxy 2... in stores. I checked Gamestop and Disc Re-play and each used copy was $48 compared to $50 new. No it isn't 100+ but still it was more than I was willing to pay. Especially since Galaxy 1 is $15 or below.
Used RPGs, especially ones that are sold in limited quantities, sell for alot online. Must I even bring up Suikoden 2, Dragon Quest 3, or Earthbound? GBA games, although extinct, still can sell for $60+: Kirby Amazing Mirror and Super Mario 3. But this is last gen, Xenoblade is probably the most expensive Wii game I bought because I was stupid and didn't go out to buy it at release.