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Mr Khan said:

I have decided that i rather hate Brachydios now. Which is good, as i'm getting over Rathalos/Rathian.

Always seems like he sticks me with that explosive goo, then when i de-equip to get it off, he just pounces on me with that explosive pounce, killed me twice in a row with that, and i just abandoned the quest rather than fail and lose those Cool Drinks...

Antiseptic skill prevents the goo from sticking in the first place.  But it sounds like you're using a non-rolling weapon like a Lance?  I switched to Long Sword and it went really smoothly, no trouble with him since.  Well, the two G-rank Brachys urgent quest was pretty nerve-wracking to solo...